Dr Richard Charlesworth
Lecturer in Biomedical Science - School of Science and Technology
Richard was conferred a PhD in Clinical Immunology in 2017 and then accepted a lecturing position at the University of New England shortly afterwards. He lectures mainly in human gastroenterology and immunology across the schools of Biomedical Science, Medicine and Nursing at the University.
Richard's research focuses on gastrointestinal immunopathology and clinical/translational immunology. Using this data, Richard is also involved in developing novel diagnostics for coeliac disease in particular, as well as developing novel therapeutic agents to treat other mucosal autoimmune diseases. More recently, Richard has joined a research group examining the bi-directional communication between the gut microbiome and the brain.
BBiomedSc, BSc (Hons), PhD, FHEA
Human physiology: gastroenterology, immunology and haematology.
Primary Research Area/sGastroenterology; Infectious and Inflammatory Bowel Disease
Richard’s main research interest is in mucosal immunology, examining how the innate and adaptive immune systems interact with exogenous antigens on a daily basis. His research is also focussed on the implementation of statistical modelling and prediction algorithms to improve the diagnosis of autoimmune disease.
Selected Recent Publications
Winter G, Hart RA, Charlesworth RPG and Sharpley C (2020) Gut Microbiome and Depression: Bidirectional Communication and Implications for Treatment, The Oxford Handbook of the Microbiome-Gut-Brain Axis, https://doi.org/10.1093/oxfordhb/9780190931544.013.6
Nazir S, Charlesworth RPG, Walkden-Brown SW and Gerber P (2020) A Melanin Bleaching Method to Prevent Non-Specific Immunostaining of Chicken Feathers, MethodsX, https://doi.org/10.1016/j.mex.2020.100957
Charlesworth RPG (2020) Diagnosing Coeliac Disease: Out with the Old and in with the New?, World Journal of Gastroenterology, 26(1): 1-10
Charlesworth RPG, Marsh MN. (2019) From 2-dimensional to 3-dimensional: Overcoming Dilemmas in Intestinal Mucosal Interpretation, World Journal of Gastroenterology, https://doi: 10.3748/wjg.v25.i20.2402
Charlesworth RPG, Agnew LL, Scott DR, and Andronicos NM. (2019) Equations Defined using Gene Expression and Histological Data Resolve Coeliac Disease Biopsies within the Marsh Score Continuum. Computers in Biology and Medicine, https://doi.org/10.1016/j.compbiomed.2018.10.036
Charlesworth RPG, Agnew LL, Scott DR, and Andronicos NM. (2018) Celiac disease gene expression data can be used to classify biopsies along the Marsh score severity scale. Journal of Gastroenterology and Hepatology, https://doi.org/10.1111/jgh.14369.
Winter, G., Hart, R. A., Charlesworth, R. P., & Sharpley, C. F. (2018). Gut microbiome and depression: what we know and what we need to know. Reviews in the Neurosciences. DOI: https://doi.org/10.1515/revneuro-2017-0072
Charlesworth RPG, Andronicos NM, Scott DR, McFarlane JR and Agnew LL, 2017, Can the Sensitivity of the Histopathological Diagnosis of Coeliac Disease be Increased and can Treatment Progression be Monitored using Mathematical Modelling of Histological Sections? – A Pilot Study, Advances in Medical Sciences, 62 (1) 136 - 142
Australasian Society for Immunology (ASI)
British Society for Immunology (BSI)