Dr Adam Rosser

Lecturer , Chemistry - School of Science and Technology

Phone: +61 02 6773 1785

Biography

Adam has been involved in teaching chemistry and forensic science at UNE since 2007 in many roles and at many levels. Currently, Adam is on a fixed-term contract for the position of Lecturer in Chemistry at UNE. Since completing a BSc(Hons) at UNE, Adam has recently completed a PhD in physical organic chemistry under the supervision of Prof Steve Glover and A/Prof Chris Fellows.

Adam’s research is currently focused on the application of quantum chemical calculations to real systems to better understand the stereoelectronic effects governing their structure and reactivity. Of particular interest are anomeric amides, a novel and fascinating class of amide discovered here at UNE. These amides exhibit unusual structure and reactivity, and have potential applications as antibiotics and cancer chemotherapy drugs. Research in this area can inform organic synthesis and drug design, and help to build a better understanding of macromolecules like proteins and synthetic polymers. Adam is open to and interested in interdisciplinary research projects.

Several research avenues are available for prospective students to consider, particularly in the field of laboratory based physical organic chemical investigations of anomeric amides, including: synthesis of novel anomeric amides, acid/base-catalysed decompositions of known and new anomeric amides, and synthesis and antibiotic screening of anomeric amides.

Qualifications

BSc(Chemistry), BSc(Hons), PhD

Teaching Areas

Adam is currently teaching Science in Practice (SCI100) and Chemistry (CHEM110).

Research Interests

Adam's research is focused on computational investigations of amidicity and stereoelectronic effects in anomeric amides, and stereoelectronic effects in levoglucosenone derivatives. Results from these investigations are being studied in conjunction with laboratory results and will be used to inform future laboratory investigations.

Adam is also interested and involved in the field of chemical education.

Publications

1.Glover, S. A.; Rosser, A. A., Heteroatom substitution at amide nitrogen-resonance reduction and HERON reactions of anomeric amides. Molecules 2018, 23 (11), 2834/1-2834/39.

2.Glover, S. A.; Rosser, A. A., The role of substituents in the HERON reaction of anomeric amides. Can. J. Chem. 2016, 94 (12), 1169-1180.

3.Glover, S. A.; Rosser, A. A., HERON reactions of anomeric amides: understanding the driving force. J. Phys. Org. Chem. 2015, 28, 215-222.

4.Glover, S. A.; Rosser, A. A.; Spence, R. M., Studies of the Structure, Amidicity, and Reactivity of N-Chlorohydroxamic Esters and N-Chloro-β,β-dialkylhydrazides: Anomeric Amides with Low Resonance Energies*. Aust. J. Chem. 2014, 67, 1344-1352.

5.Glover, S. A.; Rosser, A. A.; Taherpour, A.; Greatrex, B. W., Formation and HERON Reactivity of Cyclic N,N-Dialkoxyamides. Aust. J. Chem. 2014, 67, 507-520.

6.Oliver, J. D.; Rosser, A. A.; Fellows, C. M.; Guillaneuf, Y.; Clement, J.-L.; Gaborieau, M.; Castignolles, P., Understanding and improving direct UV detection of monosaccharides and disaccharides in free solution capillary electrophoresis. Anal Chim Acta 2014, 809, 183-93.

7.Glover, S. A.; Rosser, A. A., Reliable Determination of Amidicity in Acyclic Amides and Lactams. The Journal of Organic Chemistry 2012, 77 (13), 5492-5502.

8.Glover, S. A.; White, J. M.; Rosser, A. A.; Digianantonio, K. M., Structures of N,N-Dialkoxyamides: Pyramidal Anomeric Amides with Low Amidicity. J. Org. Chem. 2011, 76, 9757-9763.

9.Digianantonio, K. M.; Glover, S. A.; Johns, J. P.; Rosser, A. A., Synthesis and thermal decomposition of N,N-dialkoxyamides. Org. Biomol. Chem. 2011, 9, 4116-4126.

10.Johns, J. P.; van Losenoord, A.; Mary, C.; Garcia, P.; Pankhurst, D. S.; Rosser, A. A.; Glover, S. A., Thermal Decomposition of N-Acyloxy-N-alkoxyamides - a New HERON Reaction. Aust. J. Chem. 2010, 63, 1717-1729.

11.Tucker, D. J.; Wallis, I. R.; Bolton, J. M.; Marsh, K. J.; Rosser, A. A.; Brereton, I. M.; Nicolle, D.; Foley, W. J., A Metabolomic Approach to Identifying Chemical Mediators of Mammal-Plant Interactions. J. Chem. Ecol. 2010, 36 (7), 727-735.

Memberships

MRACI