Application procedures list
This information relates to Question B7 on the AEC application form.
Researchers are requested to bold the most appropriate section in the table in question B7 of the AEC application form. This purpose should reflect the primary procedure of the protocol only.
Observation Involving Minor Interference
Animals are not interacted with or, where there is interaction, it would not be expected to compromise the animal’s welfare any more than normal handling, feeding, etc. There is no pain or suffering involved.
Animal Unconscious Without Recovery
Animal is rendered unconscious under controlled circumstances with little or no pain or distress. Capture methods are not required. Any pain is minor or brief and does not require analgesia. Procedures are carried out on the unconscious animal which is then killed without regaining consciousness.
Minor Conscious Intervention
Animal is subjected to minor procedures which would normally not require anaesthesia or analgesia. Any pain is minor and analgesia usually unnecessary, although some distress may occur as a result of trapping or handling.
Minor Surgery With Recovery
Animal is rendered unconscious with as little pain or distress as possible. A minor procedure such as cannulation or skin biopsy is carried out and the animal is allowed to recover. Depending on the procedure, pain may be minor or moderate and post-operative analgesia may be appropriate. Field capture using chemical restraint methods is also included here.
Major Surgery With Recovery
Animal is rendered unconscious with as little pain or distress as possible. A major procedure such as abdominal or orthopaedic surgery is carried out and the animal is allowed to recover. Post operative pain is usually considerable and at a level requiring analgesia.
Minor Physiological Challenge
Animal remains conscious for some or all of the procedure. There is interference with the animal’s physiological or psychological processes. The challenge may cause only a small degree or pain/distress or any pain/distress is quickly and effectively alleviated.
Major Physiological Challenge
Animal remains conscious for some or all of the procedure. There is interference with the animal’s physiological or psychological processes. The challenge may cause only a moderate or large degree or pain/distress which is not effectively alleviated.
Death As An Endpoint
This category only applies in those rare cases where the death of an animal is a planned part of the procedures and animals die but are not euthanased. Where predictive signs of death have been determined and euthanasia is carried out before significant suffering occurs, they may be placed in category 6 or 7.
It does not include: death by natural causes; animals which are euthanased as part of the project; animals which are euthanased if something goes wrong; animals euthanased for dissection or for use as museum specimens; or accidental deaths.
Production Of Genetically Modified Animals
This category is intended to allow for the variety of procedures which occur during the production of genetically modified animals. As animals in this category may be subjected to both minor and major physiological challenges and surgical procedures, this category reflects the varied nature of the procedures carried out. It effectively includes ALL animals use in GM productions other than the final progeny which are used in a different category of procedure.