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Nicola King

Senior Lecturer, School of Science and Technology

Qualifications

BSc (Hons) (Napier University), PhD (University of Newcastle Upon Tyne)

Contact

Email:
Room: McClymont Building (W34)
Phone: 02 6773 2579 (or +61 2 6773 2579 overseas)
Fax: 02 6773 3267

Upon completion of her PhD Nicola began her long and successful association with the University of Bristol, firstly within the Department of physiology and then the Bristol Heart Institute. During this time, she was awarded prestigious fellowships from The British Heart Foundation which she used to characterise acidic amino acid transport in heart and to reveal the potential of acidic amino acids as myocardial anti-oxidants. Just prior to joining UNE, Nicola held a lecturing position at the Universiti Brunei Darussalam where she was involved in medical education and the development of a new degree program.

Affiliations

Executive Board Member: British Society for Cardiovascular Research (2006-2009)
Elected member of The Physiological Society
Member British Society for Cardiovascular Research

Research interests

  • Oxidative stress and anti-oxidant status in heart
  • Physiological vs. pathological cardiac hypertrophy
  • Myocardial protection
  • Cardiac amino acid and dipeptide transport
  • Interprofessional medical education

Teaching

  • Human physiology
  • Human biology

Selected publications

Nicola King (editor), RT-PCR Protocols (2nd Edition) Met Mol Biol, Springer, New York, USA, in press.

King N., The use of comparative quantitative RT-PCR to measure the effect of cysteine incubation on GPx1 expression in isolated cardiomyocytes, Met Mol Biol., in press.

King N., Amino acids and mitochondria, in Mitochondria: the dynamic organelle from the series Advances in Biochemistry in Health and Disease, S Schaffer and M-S Suleiman (eds.), Springer, New York, USA. ISBN: 978-0-387-69944-8, 2007.

King N., Measurement of cardiac gene expression by reverse transcription polymerase chain reaction (RT-PCR), Met Mol Biol, 366, pp. 109-119, 2007.

Lin H. and King N., Demonstration of functional dipeptide uptake into freshly isolated guinea-pig cardiomyocytes, Pflügers Arch., 453, pp. 915-922, 2007.

King N., Lin H., McGivan J.D. and Suleiman M.- S., Glutamate transporter activity in hypertrophic rat heart and ischaemia-reperfusion injury, Pflügers Arch, 452, pp. 674-682, 2006.

Shackebaei D., King N., Shukla B. and Suleiman M.- S, Mechanisms underlying the cardioprotective effect of L-cysteine, Mol Cell Biochem, 277, pp. 27-31, 2005.

King N., Lin H., McGivan J.D. and Suleiman M.- S., Aspartate transporter activity in hypertrophic rat heart and ischaemia-reperfusion injury, J. Physiol., 556, pp. 849-858, 2004.

King N., Korolchuk S., McGivan J.D. and Suleiman M.- S., A new method of quantifying glutathione levels in freshly isolated single superfused rat cardiomyocytes, J. Toxicol. Pharmacol. Methods, 50, pp. 215-222, 2004.