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Brian Cheetham

Associate Professor, School of Science and Technology

Contact

Email: bcheetha@une.edu.au
Room: McClymont Building 329
Phone: 02 6773 3394 (or +61 2 6773 3394 overseas)
Fax: 02 6773 3267

Additional:
Biosafety Officer

I completed a B.Sc.(Hons) degree with a major in Biochemistry at the Australian National University. For my Ph.D. I worked on biochemical aspects of the interactions between adenoviruses and the cell cycle at the John Curtin School of Medical Research, ANU. I continued my interest in the cell cycle at the University of California, Santa Barbara, where I studied genes which control cell cycle progression in yeast. I then took a position at Monash University with a major research focus on the role of the interferon system in diseases such as lupus, multiple sclerosis, rheumatoid arthritis and hepatitis B. I came to UNE in 1991 and my major research focus has been the use of molecular biology to study footrot infections in sheep.

Research interests

My major current research interest is the molecular analysis of the anaerobic bacterium Dichelobacter nodosus, which causes footrot in sheep. I am also involved with collaborative projects on the molecular genetics of fungi and the use of molecular biology for the diagnosis of viral diseases of poultry.

Teaching

I teach introductory metabolism in BIOL110, gene regulation in BCHM210, DNA technology in BCHM330 and virology in MICR350.

Selected publications

Katz M.E., Evans C.J., Heagney E.E., vanKuyk P.A., Kelly J.M. and Cheetham B.F., A possible role for vesicular trafficking in nutrient sensing in Aspergillus nidulans, Genetics, 2009, in press.

Chousalkar K.K., Roberts J.R. and Cheetham B.F., Effects of Australian infectious bronchitis virus on the oviduct of commercial laying hens vaccinated in the rearing phase, Vaccine, 2009, in press.

Chousalkar K.K., Cheetham B.F. and Roberts J.R., LNA probe-based real time RT-PCR for the detection of infectious bronchitis virus from the oviduct of unvaccinated and vaccinated laying hens, J. Virol. Meth., 155: 67-71, 2009.

Katz M.E., Bernardo S.M. and Cheetham B.F., The interaction of induction, repression and starvation in the regulation of extracellular proteases in Aspergillus nidulans: evidence for a role for CreA in the response to carbon starvation, Curr Genet., 54: 47-55, 2008.

Cheetham B.F., Parker D., Bloomfield G.A., Shaw B.E., Sutherland M., Hyman J.A., Druitt J., Kennan R.M., Rood J.I. and Katz M.E., Isolation of the bacteriophage DinoHI from Dichelobacter nodosus and its interactions with other integrated genetic elements, Open Microbiol, J. 2: 1-9, 2008.

Bernardo S.M.H., Gray K.-A., Todd R.B., Cheetham B.F. and Katz M.E., Characterization of regulatory non-catalytic hexokinases in Aspergillus nidulans, Mol. Gen. Genomics, 277: 519-532, 2007.

Cheetham B.F., Tanjung L.R., Sutherland M., Druitt J., Green G., McFarlane J., Bailey G.D., Seaman J.T. and Katz M.E., Improved diagnosis of virulent ovine footrot using the intA gene, Vet. Microbiol., 116: 166-174, 2006.

Katz M.E., Gray K.A. and Cheetham B.F., The Aspergillus nidulans xprG (phoG) gene encodes a putative transcriptional activator involved in the response to nutrient limitation, Fungal Genetic Biol., 132: 127-34, 2006.

Renz K.G., Islam A., Cheetham B.F. and Walkden-Brown S.W., Absolute quantification using real-time polymerase chain reaction of Marek's disease virus serotype 2 in field dust samples, feather tips and spleens, J. Virol. Meth., 135: 186-191, 2006.

Islam A., Cheetham B.F., Mahony T.J., Young P.L. and Walkden-Brown S.W., Absolute quantification of Marek's disease virus and Herpesvirus of turkeys in chicken lymphocyte, feather tip and dust samples using real-time PCR, J. Virol. Meth., 132: 127-134, 2006.