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BCHM310 Proteins - The Machines of Life

Updated: 01 November 2011
Credit Points 6
Offering
Responsible Campus Teaching Period Mode of Study
Armidale Trimester 1 Off Campus
Armidale Trimester 1 On Campus
Intensive School(s)
Start Finish Attendance Notes
23 March 2012 26 March 2012 Mandatory On-campus students to attend intensive school.
Supervised Exam There is a UNE Supervised Examination held at the end of the teaching period in which you are enrolled.
Pre-requisites BCHM210 or BCHM210A or candidature in a postgraduate award in the School of Environmental and Rural Science or School of Science and Technology
Co-requisites None
Restrictions BCHM310A or BCHM510
Notes None
Combined Units BCHM510 - Proteins - The Machines of Life
Coordinator(s) Heather Nonhebel (hnonheb2@une.edu.au)
Unit Description

This unit focuses on protein structure and function, and analysis of proteins in the laboratory and by computer. Topics studied will include: an examination of protein structure and structural analysis; the relationship between protein structure and function in living organisms, studied using current examples; an introduction to protein evolution; the formation and degradation of native proteins in the cell including the targeting and post-translational processing of proteins; an introduction to protein engineering. Practical work will include protein isolation and assay; and introduction to protein databases. BCHM510 will cover material in greater depth than BCHM310, with separate assessments being completed.
Prescribed Material
Mandatory 		Text(s):

Note: Students are expected to purchase prescribed material

Biochemistry
ISBN: 9780470570951
Voet, D. and Voet, J.G., Wiley 4th ed. 2010
Text refers to: Trimester 1 , On and Off Campus
Disclaimer Unit information may be subject to change prior to commencement of the teaching period.
Assessment
Title Exam Length Weight Mode No. Words
Assignment 1 10%
Assessment Notes
Bioinformatic analysis of protein sequences. It is mandatory to pass this component in order to pass the unit.
Relates to Learning Outcomes (LO) and Graduate Attributes (GA)
LO: 6 GA: 1, 2, 4, 6
Assignment 2 20% 2000
Assessment Notes
Protein isolation assignment It is mandatory to pass this component in order to pass the unit.
Relates to Learning Outcomes (LO) and Graduate Attributes (GA)
LO: 5 GA: 1, 2, 4, 6
Laboratory Work 5%
Assessment Notes
Laboratory skills and tutorial participation
Relates to Learning Outcomes (LO) and Graduate Attributes (GA)
LO: 2, 5 GA: 1, 2, 4, 6, 7, 8
Quiz 5%
Relates to Learning Outcomes (LO) and Graduate Attributes (GA)
LO: 1 GA: 1, 6
Report 15% 1500
Assessment Notes
Practical report
Relates to Learning Outcomes (LO) and Graduate Attributes (GA)
LO: 5 GA: 1, 2, 4, 6
Final Examination 2 hrs 45%
Assessment Notes
It is mandatory to pass this component in order to pass the unit.
Relates to Learning Outcomes (LO) and Graduate Attributes (GA)
LO: 1, 2, 3, 4 GA: 1, 2, 6

Learning Outcomes (LO) Upon completion of this unit, students will be able to:
  1. understand basic principles of protein structure;
  2. use current examples to illustrate in detail the relationship between protein structure and function in a living organism;
  3. appreciate evolutionary relationships between proteins;
  4. describe how proteins are directed to cellular compartments, modified following translation, assisted to fold into their native state and specifically degraded;
  5. handle and assay proteins in the laboratory and be able to design protein isolation protocol; and
  6. use a range of bioinformatic tools relating to proteins.

Graduate Attributes (GA)
Attribute Taught Assessed Practised
1 Knowledge of a Discipline
This unit focuses on protein structure and function, and analysis of proteins in the laboratory and by computer. Topics studied will include: an examination of protein structure and structural analysis; the relationship between protein structure and function in living organisms, studied using current examples; an introduction to protein evolution; the formation and degradation of native proteins in the cell including the targeting and post-translational processing of proteins; an introduction to protein engineering. Practical work will include protein isolation and assay; and introduction to protein databases. 		True True True
2 Communication Skills
Essay writing and scientific report writing are taught practised and assessed. 		True True True
4 Information Literacy
Students are instructed on methods for accessing relevant scientific literature, databases and websites; this is practised and assessed in assignments and practical report. Students discuss two scientific journal articles in depth during an assessable tutorial/discussion session. 		True True True
5 Life-Long Learning
Students learn that scientific knowledge is constantly changing and requiring constant updating. 		True
6 Problem Solving
The two major assignments in this unit are students are complex problem solving exercises. 		True True True
7 Social Responsibility
Scientific ethics are taught practised and assessed in practicals. 		True True
8 Team Work
Students must work cooperatively in order to complete practical work. 		True True
   

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