Bioinformatics is a broad interdisciplinary science that involves conceptual and practical tools for understanding, generation, processing and propagation of biological information. It covers relevant areas of statistics and computer science, biological databases, computational genomics and phylogenetics. The unit is designed for students with appropriate statistics and computing skills. The topics covered include Hidden Markov Models, dynamic programming, biological database operations, sequence search and alignments, gene detection and prediction, computational genomics and proteomics, microarrays and phylogenetic analysis. Besides solid theoretical knowledge students will receive good practical experience in modelling, computing and interpreting information in modern biological databases.